A sudden outbreak of meningitis strikes the town, overwhelming the local clinic. Tensions rise as supplies run low and residents fear the disease will spread uncontrollably within the enclosed space.

One of the episode’s tensest subplots involves Junior keeping Angie trapped in an underground shelter. By the end of the episode, Big Jim makes a discovery that complicates his relationship with his son.

In this episode, the trapped residents of Chester's Mill face their first major medical crisis since the dome descended.

You might be referring to the iconic nu-metal song " Down With the Sickness " by Disturbed , known for its "ooh-wah-ah-ah-ah" intro.