The text covers the fundamental methods used in molecular diagnostics, including:
Reviews the structure and function of DNA, RNA, and proteins, covering topics such as replication, transcription, and translation.
Discusses the application of molecular diagnostics to infectious diseases, oncology, human identification (forensics/paternity), and inherited disease diagnosis. Key Features of the Text Molecular Diagnostics: Fundamentals, Methods, &...
Includes learning objectives, key terms, and review questions at the end of each chapter.
Highlights advanced, in-depth material to challenge students. The text covers the fundamental methods used in
Contains over 300 line drawings and color plates illustrating molecular concepts. Key Techniques Discussed
Covers nucleic acid extraction methods, electrophoresis, hybridization technologies, restriction enzyme mapping, and amplification techniques (PCR, NASBA). Highlights advanced, in-depth material to challenge students
Molecular Diagnostics: Fundamentals, Methods, & Clinical Applications by Lela Buckingham (and Maribeth L. Flaws in earlier editions) is a leading textbook designed for clinical laboratory science students and professionals, with a new 4th edition published in February 2026. It provides a foundational understanding of nucleic acid biochemistry, common laboratory techniques, and the clinical application of molecular-based assays. Core Areas Covered