Research published around May 2022 explored the impact of "early" vs. "late" discontinuation (stopping before or after 3 years), noting that early stopping is often forced by toxicity rather than choice.
Patients are encouraged to discuss the balance between disease control and the toxic long-term effects of maintenance drugs with their oncology team. IFM_05-May 2022
A significant number of patients (roughly 27%) had to stop the maintenance therapy early due to adverse side effects. Research published around May 2022 explored the impact
Early versus Late Discontinuation of Maintenance Therapy in ... - MDPI A significant number of patients (roughly 27%) had
If you are looking for guidance based on this study's results:
The study demonstrated a clear overall survival benefit for patients receiving maintenance therapy compared to a placebo.
Due to the risk of secondary cancers identified in the IFM-05 trial, long-term monitoring for new symptoms or blood changes is standard practice for those on this regimen.