: Most drugs flood the brain's reward circuit with dopamine, creating euphoria.
: Over time, the brain reduces its natural dopamine production, leading to tolerance —the need for higher amounts of a substance to achieve the same effect. drug and alcohol abuse
Substance use disorders (SUD) typically manifest through a combination of physical, behavioral, and psychological symptoms. : Most drugs flood the brain's reward circuit
Addiction is defined as a characterized by compulsive seeking and use of substances despite harmful consequences. creating euphoria. : Over time