Bmp4 -

: It primarily signals through two routes:

BMP4 is synthesized as a 408-residue preproprotein that undergoes specific proteolytic cleavage to become a mature 116-residue active peptide. : It primarily signals through two routes: BMP4

: It initiates bone and cartilage development and is particularly critical for patterning teeth. Mutations in BMP4 are linked to tooth agenesis (missing teeth). : It primarily signals through two routes: BMP4