Athena Heart [310] Online

Stop other Class I or III antiarrhythmics (e.g., amiodarone, sotalol) before starting Multaq. Avoid strong (e.g., ketoconazole).

The official FDA label outlines critical safety measures based on ATHENA data: :

: Monitor serum creatinine levels; small increases are common but should be assessed if they persist. ATHENA HEART [310]

: Do not use in patients who cannot or will not be converted to sinus rhythm.

Monitor closely if the patient is also taking warfarin, as dronedarone can increase warfarin exposure. 4. Patient Monitoring Stop other Class I or III antiarrhythmics (e

The ATHENA trial was a landmark study that evaluated the efficacy of dronedarone in reducing cardiovascular hospitalizations or death.

Following the ATHENA results, dronedarone was approved with specific administration and safety protocols. : The only recommended dose is 400 mg twice daily . : Do not use in patients who cannot

: Contraindicated in patients with symptomatic heart failure or recent hospitalization for heart failure (NYHA Class IV or symptomatic Class II-III).