: Without proper Chmp4c function, cells often experience errors in chromosome alignment, leading to genomic instability.
: Showing the progression of a cell through mitosis. 39091.mp4
: The paper demonstrates that Chmp4c is required for the proper timing of mitosis; its absence can cause a significant delay in the cell cycle. Significance of the .mp4 File : Without proper Chmp4c function, cells often experience
The study investigates the role of , a protein traditionally known for its function in the ESCRT-III (Endosomal Sorting Complex Required for Transport) pathway, which typically handles late-stage cell division (abscission). The researchers discovered that Chmp4c has a much earlier role: : Without proper Chmp4c function
: Visualizing how the spindle forms and interacts with chromosomes in both control cells and Chmp4c-depleted cells to illustrate the paper's findings.