22948 Rar May 2026

: It is most famous for its role in Acute Promyelocytic Leukemia (APL) . In most cases of APL, a piece of chromosome 15 (containing the PML gene) and a piece of chromosome 17 (containing the RARA gene) swap places. This creates a fusion protein called PML-RARA , which prevents immature white blood cells from maturing properly.

: RARA acts as a transcription factor. When it binds to Retinoic Acid (a derivative of Vitamin A), it regulates the expression of genes involved in cell growth, differentiation, and development. 22948 rar

If you tell me more about your specific interest in this gene, I can provide: on its role in embryogenesis. Details on other RAR types (beta or gamma). Information on drug interactions targeting this receptor. : It is most famous for its role