According to recent studies from the NIH HIV Reagent Program and the American Society for Microbiology , tazarotene acid is being investigated for the following:
Tazarotene acid is the active carboxylic acid metabolite of the prodrug tazarotene [21]. It functions as a selective retinoid X receptor (RXR) and retinoic acid receptor (RAR) agonist, specifically targeting and RAR- [14]. Key Research Applications 21367.rar
: Research indicates it significantly enhances Natural Killer (NK) cell natural cytotoxicity and antibody-dependent cellular cytotoxicity (ADCC) against HIV-infected CD4 T cells [14, 21]. According to recent studies from the NIH HIV
Elimination of latent HIV reservoirs and dermatological efficacy [14] 21367.rar
: It has been identified as a compound capable of sensitizing latently infected HIV cells to apoptosis [14, 21].